THE NEUROLOGIC PAIN BLOG

Evidence-Based Insights for People With Complex & Persistent Pain


with Dr. Alissa Wolfe, PT, DPT, OMPT, OCS, CHC, TPS

Arthritis and Degenerative Changes: Why Your Pain Is Two Problems, Not One

arthritis pain bone on bone degenerative changes nerve sensitivity osteoarthritis

You've seen the X-ray. Maybe the word was "bone on bone." Maybe it was osteoarthritis in your knees, hips, or hands, or degenerative changes with bone spurs. And maybe you were told, directly or not, that the only real options left are more physical therapy, more injections, or eventually a joint replacement.

Here's what that conversation usually leaves out: the structural changes are real, but they are not the only thing producing your pain. The pathways that carry and process pain signals can keep firing at a level the joint itself doesn't explain. And that part can change, even when the X-ray doesn't.

Why Arthritis Pain Doesn't Always Match the Imaging

Most of the women I talk to have an above-average understanding of anatomy. Over years of appointments they've learned about cartilage, discs, ligaments, tears, bone spurs, and joint space. They can tell you exactly what their imaging shows.

That makes sense. We're taught about the parts we can see on X-rays and MRIs and the parts a chiropractor, PT, or massage therapist can feel with their hands.

What we're not taught about is the activity in the nervous system: the synapses, the chemical messengers, and the brain's processing of every signal coming from that joint. An X-ray shows structure. It does not show how sensitive the system reading that structure has become.

Just because those changes don't appear on imaging doesn't mean they aren't part of the pain problem. With long-standing arthritis, they very often are.

For complex and persistent pain

Something is being missed.

The Uprising: Complex Pain Academy is a structured, 5-phase program that targets the neurologic sensitivity behind persistent pain, in the right order and at the right dose, with a specialist guiding every step.

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"But I Know What's Causing My Pain"

One woman I worked with came to me after years of wear and tear. She wanted to get stronger, stay active, and keep up with her grandkids. When I explained that recovery would involve understanding pain differently, she pushed back right away: she knew exactly what was causing her pain. She had multiple disc herniations and bone spurs in her lower back, and they were pressing on a nerve.

She was right that those findings were real and significant. She was skeptical of anything involving the nervous system because her pain wasn't "mind-body." She had real physical problems.

Both things were true. Her structural changes played a real role in her pain. And there wasn't much more that could be done about them. She had already been through surgery and physical therapy, more than once.

What changed for her was learning that she could tackle the problem from a different angle, and that this angle didn't require reprocessing emotions or talking herself out of pain. Within a matter of weeks, her worst pain went from a 9 out of 10 to a 5, with the same arthritic and degenerative changes still in place.

Structural Damage and Pain Sensitivity Are Two Different Problems

It's easy to assume pain can't improve unless the physical problem is fixed. But even if the structural problem could be completely resolved, pain often persists, because the nervous system has also changed.

Think about what happens after an amputation. The leg is gone, but the leg in the brain is still there. The pathways and connections that represented that limb are still active, and sometimes they keep firing even though no signals are coming from a limb at all. That's phantom limb pain. The structure is completely gone, and the pain is still real, because it's being generated by pathways that have adapted.

Arthritis works on the same principle in a less dramatic way. Years of pain from a joint change the way the system processes signals from that joint. Over time, those pathways can become overactive, firing more readily and more intensely than the joint's condition warrants. That's neurologic sensitivity, and it sits on top of the structural problem.

Which means you're dealing with two problems:

  • The structural changes in the joint, which are real and largely fixed in place.
  • Overactive pain pathways, which are adaptable and can settle.

Most treatment for arthritis targets only the first. The second is where much of the opportunity is.

Why More of the Same Hasn't Worked

If you have arthritis or degenerative changes in your knees, hips, hands, or spine, you've probably been offered some combination of pain medication, injections, physical therapy exercises, and surgery. Each of these targets the joint.

When the joint isn't the only thing driving the pain, each of these can help a little and still leave you stuck. Strengthening can flare a sensitive system. Injections can wear off. Surgery can change the structure and leave the sensitivity untouched. And if you've had several rounds of the same approach, another round is unlikely to produce a different result. It's the same pattern I see with degenerative disc disease in the spine: the imaging gets the attention, and the signaling system gets ignored.

Lowering Sensitivity Without Changing the Structure

Addressing neurologic sensitivity is a way to reduce arthritis pain that doesn't rely on more pills, procedures, endless exercises, or irreversible surgery. It works alongside the structural reality instead of waiting for it to change.

That doesn't mean spending hours in the gym pushing into flares. It doesn't mean becoming a mind-body healer, either. It means working directly with the pathways that have become overactive, using methods like pain neuroscience education, graded motor imagery, sensory discrimination, and neurodynamic techniques, with strengthening layered in once sensitivity has settled enough to tolerate it.

The principle is push to it, not through it. Forcing activity through high pain feeds the sensitivity you're trying to lower. Building gradually up to the edge of what your system tolerates is what lets it adapt.

The methods themselves are only part of it. The order they're used in, the dose, and how they're adjusted to your system decide whether they lower sensitivity or provoke a flare. That's what a structured plan provides, and it's why randomly adding a new exercise rarely changes much.

Bone on Bone Is Not the End of the Conversation

"Bone on bone" sounds final. For the joint, in many ways, it is. But your pain is not determined by your X-ray alone. Even with significant, permanent structural changes, there is a second factor in your pain that can change. Addressing it is how you regain quality of life without waiting on the joint.

Not sure which dimension is driving your pain? Take the free Pain Profile quiz and get three separate scores: physical, neurologic sensitivity, and mental/emotional.

If neurologic sensitivity turns out to be the driver, that's exactly what The Uprising: Complex Pain Academy is built to address.

FREE SELF-ASSESSMENT

The 3-Dimensional Pain Profile Quiz

 
Discover what's influencing your pain (and where to focus) with separate scores in three different dimensions: physical + mental/emotional + neurologic sensitivity.

Take the Quiz

Hi, I'm Dr. Alissa Wolfe

PT, DPT, OMPT, OCS, CHC, TPS

I'm a board-certified orthopedic doctor of physical therapy, but I specialize in complex and persistent pain.

My focus is on the neurologic wiring between the structures of the body and the mind — the missing piece most treatments overlook.

I've been building pain programs across the US since 2016 — including one for the US Army — because I kept seeing the same gap: smart, motivated people doing everything they were told, and still not getting better.

In 2021 I founded The Uprising: Complex Pain Academy to fill the gap the medical system has left wide open.

Now, I work exclusively with people who have complex pain that hasn't responded to standard treatments, providing the structure, guidance, and relief they've been searching for.

Learn about the Program